Desiccated thyroid extract compared with levothyroxine in the treatment of hypothyroidism: a randomized, double-blind, crossover study. A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.' Or, if fluoride, mercury, or any number of xenobiotic chemicals in the environment requiring selenium-dependent glutathione-mediated detoxification is causing the low thyroid, why call chemical poisoning hypothyroidism? [9] [10] [11] Although we should never forget that LT4 is a life-saving thyroid hormone replacement, and that one should not exclude that the pathological reason that leads to the prescription of LT4 could favor the lung cancer development also. Post I'm not saying that there Is no link between Synthroid and lung cancer. Thyroid dysfunction after immune checkpoint inhibitor treatment in a Brit Med J 1978, 1:210212. The great open sky of imagination: for those who u Fermented Foods: Top 8 Reasons to Eat Them. [4] Ratcliffe JG, Stack BH, Burt RW, Radcliffe WA, Spilg WG, Cuthbert J, Kennedy RS: Thyroid function in lung cancer. May be of interest: Study: Millions Treated for Hypothyroidism At Risk for, Non-small cell lung cancer - Adenocarcinoma, Non-small cell lung cancer - Squamous cell, Top 5 Questions to Ask Your Lung Cancer Doctor, Patient & Caregiver Network Member Resources, Not A Member Yet? Note: Only a member of this blog may post a comment. Comp Biochem Physiol C Toxicol Pharmacol 2002, 133:475481. Levothyroxine is a widely prescribed medication for the treatment of an underactive thyroid. View the data on GreenMedInfos Hypothyroidism Research page. Endocrinology 2008, 149:22412250. Furthermore, the geometric expansion of hypothyroidism cases in the past decade only thinly conceals an agenda to promote the synthetic form of T4 known as levothyroxine sodium (trade name Synthroid), since with each new disease case the patient is converted into a lifelong customer. Metab.87 (2): 48999. Cancer-related fatigue (CRF) is common in lung cancer survivors and can occur at any point in the care continuum. Intuition and Trust: a Personal Journey Through Ancient Pathways, Meditation, Yoga, Grounding & Mindfulness, Levothyroxine and lung cancer in females: the importance of oxidative stress, 2013 announcement by a National Cancer Institute, T-score based definition of osteoporosis and osteopenia, 30-billion dollar a year market in statin drugs, Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III). There are many links attached. A total of 425 inpatients with malignant tumors were treated with ICIs at PUMCH during the study period. Symptoms. ', Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer. I had doctor after doctor tell me it was in my head or I was menopausal. In discussing their findings, the authors noted that they could not exclude the possibility that the condition of hypothyroidism could favor the development of lung cancer. A place for patients and relatives. Just another excuse for keeping us on doses that are too low. They only reappear when I need to fine tune the medication. 2004 Jun;9(2):157-79. I wonder if only t3 treatments are preferable than t4 and t3 ? Brit Med J 1978, 1:210212. El almacenamiento o acceso tcnico es estrictamente necesario para el propsito legtimo de permitir el uso de un servicio especfico explcitamente solicitado por el abonado o usuario, o con el nico propsito de llevar a cabo la transmisin de una comunicacin a travs de una red de comunicaciones electrnicas. [8] This means that the amount of LT4 reaching the lungs following an external supplementation cannot to be transformed into LT3 as in the other tissues, and make lungs very vulnerable to possible toxic effects of LT4. Modern Medicine, Part I: How Healing Illness Becam Is your body getting too acidic? Given the clear role that selenium deficiency plays in preventing the conversion of T4 to the far more biologically active form of thyroid hormone known as triiodothyronine (T3), which can cause an elevation of thyroxine-stimulating hormone (TSH), why call a mineral deficiency-induced decrease in T4 a monolithic disease entity such as hypothyroidism? [2] Meng R, Tang HY, Westfall J, London D, Cao JH, Mousa SA, Luidens M, Hercbergs A, Davis FB, Davis PJ, et al: Crosstalk between integrin v3 and estrogen receptor- is involved in thyroid hormone-induced proliferation in human lung carcinoma cells. and our If people do not wish to find out all they can about their disease that is fine too. [13] Hollowell JG, Staehling NW, Flanders WD. Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer Now, I will bring it to the attention of my Endocrinologist. The article also stresses that too many people are being given the diagnosis of either hypo or hyperthyroidism. As I am the caregiver for my dad who has Stage IV lung Cancer, I hope more research can be done on this topic soon. Or, simply look at what the young-adult, T-score based definition of osteoporosis and osteopenia has done to convert millions of healthy middle-age and older women into drug-treatable patients, or, what the lipid hypothesis of cardiovascular disease causation has done to create a 30-billion dollar a year market in statin drugs, to fully appreciate the harms of overdiagnosis and overtreatment. "A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.' Study: Millions Treated for Hypothyroidism at Risk of Lung Cancer This article is copyrighted by GreenMedInfo LLC, 2013, Some features are currently member only features. I am convinced that my lung cancer is related to the thyroid/auto immune issues I've had for years. Article published in Wakeup-World.Com. (They noted that this age range corresponds to more than 80% of the consumers of the drug and to about 99% of all malignant cancers). Lung cancer survivors support group and discussion community, http://www.greenmedinfo.com/blog/study-millions-treated-hypothyroidism-risk-lung-cancers?utm_source=www.GreenMedInfo.com&utm_campaign=2189ddd3c1-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-2189ddd3c1-87046221. Curr Opin Endocrinol Diabetes Obes 2010, 17:432436. Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer Physician/Author on Facebook. They found no significant correlation between T4 sales and breast, colorectal and gastric cancers, but did find a significant correlation for lung cancer (p < 0.05) corrected for smoking and age. Objectives: To examine site-specific cancer incidence and mortality and to evaluate the radiation dose-response association after RAI treatment for hyperthyroidism. If it's high, the test is done again, along with a blood test for the thyroid hormone T-4. They also noted that oxidative stress is one of the causes of chronic diseases and cancer. Marketed as superior to traditional glandular forms extracted from pigs (whose endocrine glands are far more bioidentical than any other animal we know of) due to the dose-to-dose standardization of the so-called 'active ingredient' T4 versus the natural variations in hormone concentrations found in the 'real thing,' which incidentally contains a wide range of additional hormones including T1, T2, T3, all of which are vitally important. Angiology 2000, 51:S65S68. Indeed, research indicates that hypothyroid patients treated with T4 replacement, that is sufficient to maintain a normal serum TSH, actually have serum free T4 that is higher than in untreated normal patients and may not result in appropriately normal serum free T3 concentrations. I've been on synthroid for 20+ years, scary. As you know, I appreciate people posting links that help us learn more about lung cancer, too. millions treated for hypothyroidism at risk for lung cancer According to data from the National Health and Nutrition Examination Survey, years 1988-1994, [13] while 0.3% of the American population exhibits overt symptoms of hypothyroidism, 14 times more (4.3%) have so-called subclinical hypothyroidism only detected via blood work. Considering that the population in Italy is about 60 million people and the sales of LT4 in the country in 2010 were 17.69 million boxes (+ 6% Vs 2009), hypothyroidism, which is the main reason for the prescription, should be a real national concern (almost 0.7 boxes/women/year). However, the study looked at the incrase of ALL lung cancers, not SCLC, so that data does not correlate with this study. Do endocrine adverse events predict longer progression-free survival In 2020 alone, there were more than 2.2 million new cases and 1.8 million deaths from lung cancer globally. Subclinical hypothyroidism: When to treat | Cleveland Clinic Journal of With the 2013 announcement by a National Cancer Institutecommissioned expert panel that a variety of so-called indolent neoplasms such as ductal carcinoma in situ(DCIS) and high-grade prostatic intraepithelial neoplasia (HGPIN), formerly understood to be forms of breast and prostate cancers, respectively, should be renamed to reflect their intrinsic benignity, a veritable sea change is occurring within the conventional medical establishment. There are several books out there written about the topic. I have no further scientific evidence. This T4 blocking/endocrine-disrupting property of the synthetic form would also activate a negative feedback loop within the endocrine system, further suppressing remaining thyroid function, and resulting in the atrophy of the compromised thyroid, a iatrogenic 'self-fulfilling prophecy' if you will. 2002 Feb ;25(2):106-9. I have posted the link now. A distorted idea of human nature is sold when people are treated as "the market. Forgot account? Find how some diseases can be healed with alternative medicine, and share your experience with florence nightingale concept 2 via de boleto [2] Meng R, Tang HY, Westfall J, London D, Cao JH, Mousa SA, Luidens M, Hercbergs A, Davis FB, Davis PJ, et al: Crosstalk between integrin v3 and estrogen receptor- is involved in thyroid hormone-induced proliferation in human lung carcinoma cells. undefined will no longer be visible to you including posts, replies, and photos. Increased sensitivity to cold. Symptoms can include fatigue, shortness of breath with exercise, and decreased ability to exercise. The omnipresent environmental contaminant perchlorate, an ingredient in jet fuel, is also a primary cause of hypothyroidism, but is almost never tested for by the conventional endocrinologists in their patient evaluations. Hashimoto's disease - Symptoms and causes - Mayo Clinic Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional. Article published in Wakeup-World.Com. One of the main drawbacks of administering T4 in isolation is the possibility that it will not convert adequately to T3, and will therefore 'back up' causing excessive T4 activity, i.e. Study: Millions Treated for Hypothyroidism At Risk of Lung Cancer. But I for one, do appreciate anything that other members forward about potential links, causes, aids to healing, whatever you can them. The Flu Propaganda Matrix Continues To Promote Fea B Vitamins Slow Alzheimer's and Grey Matter Loss. The authors expanded on their findings further: "However, the impression we get from our experience in epidemiological studies monitoring[12] is that this drug should be prescribed more cautiously. [7] They also elaborate on a mechanism of T4-induced lung tissue toxicity: "[I]n rats lung the deiodination of LT4 is the lowest compared to all the other tissues. An Italian study published in the journalReproductive Biology and Endocrinology,titled Levothyroxine and lung cancer in females: the importance of oxidative stress, has raised a concerning possibility: levothyroxine (T4), one of the worlds most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low thyroid function (hypothyroidism). It is very tormenting (for me anyhow) to not know why I got this disease. A new Italian study published in the journal Reproductive Biology and Endocrinology titled, "Levothyroxine and lung cancer in females: the importance of oxidative stress," has raised a concerning possibility: levothyroxine (T4), one of the world's most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low thyroid function (hypothyroidism). bear in the big blue house characters; colne times obituaries this week Menu Toggle. Hashimoto's disease progresses slowly over the years. Other research indicating that increased thyroid activity (hyperthyroidism) contributes to lung cancer pathogenesis was presented, including: Recently T4 has been reported as one of the several endogenous factors capable of supporting proliferation of lung cancer cells. Share your experience, learn from others. Study: Millions Treated for - The Wellness Institute | Facebook Millions of people who were not only wrongly diagnosed with 'cancers' and subsequently aggressively treated for them with chemotherapy, radiation and surgery, are now being told that they would have been better left undiagnosed and untreated. [4], DI activity in lung cancer was found to be lower than in peripheral lung tissue.[5]. Kelly Mellott on LinkedIn: Nodify Lung: Nodule Risk Assessment | Biodesix 500+ pages of Natural Medicine Alternatives and Information. The authors delved deeper into the reason why oxidative stress taking place during T4 treatment is particularly linked to lung cancer only: The hypothesis could be that in lungs the increase of hypoxia-induced factor (HIF-1) which is determined by T4 can make oxygen much more available, increasing locally the oxidative stress together with a dangerous angiogenesis stimulation. By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. [8] This means that the amount of LT4 reaching the lungs following an external supplementation cannot to be transformed into LT3 as in the other tissues, and make lungs very vulnerable to possible toxic effects of LT4. Untreated hypothyroidism increases morbidity and mortality. 'A new Italian study published in the journal Reproductive Biology and Endocrinology titled, "Levothyroxine and lung cancer in females: the importance of oxidative stress," has raised a concerning possibility: levothyroxine (T4), one of the world's most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low thyroid function (hypothyroidism). Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer The study looked at the prevalence of breast, colorectal, gastric and lung cancer in 18 Italian Regions during 2010 and correlated this data with sales of LT4 in 2009, focusing on women aged 30-84. However, they pointed out that the opposite was actually described, and that hypothyroidism reduces the aggressiveness of some cancers because of the presence of thyroid hormone receptors on cancer cells, and spontaneous hypothyroidism may delay onset or reduce aggressiveness of cancers.[1]. Other research indicating that increased thyroid activity (hyperthyroidism) contributes to lung cancer pathogenesis was presented, including: The authors also cite animal experimental research which has shown that T4 increases the oxidative stress[6] and spontaneous pulmonary metastases in mice. Monaldi Arch Chest Dis 2003, 59:140145. I hope that with increased knowledge we will all find the right road. Just for entertainment value take a look at some more dodgy correlations : I rather liked the correlation between consumption of orange marmalade and birth rate - in the years after the second world war if I remember correctly. [14] In other words, you can 'normalize' the main clinically measurable parameter associated with 'low thyroid function,' i.e. In fact, a 2004 study in subjects with normal thyroid function found that administration of tyrosine leads to a significant reduction in serum TSH and improvement in mood in winter compared with placebo, while the combined synthetic T4-T3 supplement leads to a worsening of mood in summer and no improvement in winter, indicating supporting glandular function is superior to 'replacement' therapy, as well as the role seasonality may play in hormone function and hormone treatment interventions. [14] In other words, you can normalize the main clinically measurable parameter associated with low thyroid function, i.e. Post by D.ap Tue Feb 21, 2017 6:40 pm "A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and . [9] Otto T, Fandrey J: Thyroid hormone induces hypoxia-inducible factor 1 gene expression through thyroid hormone receptor /retinoid x receptor -dependent activation of hepatic leukemia factor. May be of interest: Study: Millions Treated for Hypothyroidism At Risk Unfortunately, it's quite typical. [7] They also elaborate on a mechanism of T4-induced lung tissue toxicity: [I]n rats lung the deiodination of LT4 is the lowest compared to all the other tissues. As a person with Graves Disease, I underwent 6 cycles of radio-ablation using i 131 to 'fry' my thyroid gland as surgery was deemed too risky due to the vascularity and size of my gland. elevated TSH, without actually improving the overall physiological situation, nor the patients subjective experience of well being. I do not believe in random events, of nature or otherwise. Angiology 2000, 51:S65S68. rocket fuel, pesticides, fluoride, which induce low thyroid function. Sub-laboratory hypothyroidism and the empirical use of Armour thyroid.Altern Med Rev. Once I got on the medication, the symptoms disappeared. J Exp Biol 2010, 213:28992911. 2013 May ;98(5):1982-90. Targeted therapy for lung cancer: Side effects and more Keri Topouzian, D.O. Physician/Author - Facebook The authors expanded on their findings further: However, the impression we get from our experience in epidemiological studies monitoring[12] is that this drug should be prescribed more cautiously. The authors of the study pointed out that levothyroxine (T4) treatment can lead to medication-induced (iatrogenic) thyroid over-activity (hyperthyroidism) and oxidative stress that can lead to a significant patient discomfort. El almacenamiento o acceso tcnico es necesario para la finalidad legtima de almacenar preferencias no solicitadas por el abonado o usuario. Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer. Treating Elderly for Subclinical Hypothyroidism Can Boost Mortality Rates Post author By ; Post date jaripeo hillsboro oregon 2021; what task do they have at camp westerbork on millions treated for hypothyroidism at risk for lung cancer on millions treated for hypothyroidism at risk for lung cancer The very concept of "marketing" is at odds with the real nature of these materials, which has to do with the protection and expansion of our nature and potential. They also noted that oxidative stress is one of the causes of chronic diseases and cancer. Data sources: The Medline and Cochrane Library electronic databases . Monaldi Arch Chest Dis 2003, 59:140145. As I have lung cancer and just recently was diagnosed hypothyroidI am very interested as to what you have to say about this connection.your personal insight and any books, websites would be appreciated.you may email me if you prefer. Due to excessive bot signups along with nefarious actors we are limiting forum registration. The Dangers of Tylenol: Is it Time to for the FDA Chile: Psychiatrist Leads Crusade To Legalize Mari 13 Things Sure To Slow Down Your Metabolism. LOL. The study included more than 128,000 veterans aged 18 to 26 and found that, just 30.2% of females and 18.7% of males had received HPV vaccination. [15] [16] There is also the more logical option of support the body's thyroid-hormone producing capabilities using the thyroxine precursor L-tyrosine, a basic amino acid with a relatively high margin of safety. Assessment of oxidative stress and its balance has not been taken into consideration up to now as it should be.". [11] Wan J, Chai H, Yu Z, Ge W, Kang N, Xia W, Che Y: H1F-1 on angiogenic potential in human small cell carcinoma. CRF encompasses physical, emotional, and/or cognitive tiredness; is related to cancer or cancer treatments; and interferes with multiple dimensions of health-related quality of life (1-3).CRF is poorly understood, underrecognized, and undertreated. Gestionar el consentimiento de las cookies. [3] Faber J, Poulsen S, Iversen P, Kirkegaard C: Thyroid hormone turnover in patients with small cell carcinoma of the lung. There is also compelling research indicating that desiccated thyroid extract (Armour thyroid) results in superior clinical outcomes versus the synthetic hormone, especially as concerns improved body weight. Correlation is not causation. arizona lockdown status today; tiktok unblocked from school; samantha and savannah concepcion Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer Posted on: Monday, August 12th 2013 at 7:15 am Written By: Sayer Ji, Founder A new study has. Marketed as superior to traditional glandular forms extracted from pigs (whose endocrine glands are far more bioidentical than any other animal we know of) due to the dose-to-dose standardization of the so-called active ingredient T4 versus the natural variations in hormone concentrations found in the real thing, which incidentally contains a wide range of additional hormones including T1, T2, T3, all of which are vitally important. millions treated for hypothyroidism at risk for lung cancer When a high-risk patient presents with one or more lung nodules, the path ahead and next steps seems obvious. Merck Announces Phase 3 KEYNOTE-671 Trial Met Primary Endpoint of Event However, that information will still be included in details such as numbers of replies. See more of Keri Topouzian, D.O. Risk of cancer in longterm levothyroxine users: Retrospective [11] Wan J, Chai H, Yu Z, Ge W, Kang N, Xia W, Che Y: H1F-1 on angiogenic potential in human small cell carcinoma. All the more reason to prescribe T3, I say! Hypothyroidism can also lead to swelling of the tongue, hoarse voice, and sleep apnea. [8] van Doorn J, Roelfsema F, van der Heide D: Concentration of thyroxine and 3,5,3-triiodotyronine in several rat tissue in vivo: the effect of hypothyroidism. [7] Kinoshita S, Sone S, Yamashita T, Tsubura E, Ogura T: Effects of experimental hyperand hypothyroidism on natural defense activities against Lewis lung carcinoma and its spontaneous pulmonary metastases in C57BL/6 mice. This is a news report of the research, so I can't learn the details of how the science was conducted. Whether it should be treated remains controversial. [13] Hollowell JG, Staehling NW, Flanders WD, et al. PMID 11836274. Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer I don't believe there are thousands of people on to high a dose of t4, so why does it feel they are hyper? The first blood test typically done to diagnose hypothyroidism measures the level of thyroid-stimulating hormone (TSH) in the blood. The estimated 2.3 million new cases indicate that 1 in every 8 cancers diagnosed in . In fact, it is the high levels of T4 that make them more susceptible to cancer. ", That study is like a fishing expedition. millions treated for hypothyroidism at risk for lung cancer Considering that the population in Italy is about 60 million people and the sales of LT4 in the country in 2010 were 17.69 million boxes (+ 6% Vs 2009), hypothyroidism, which is the main reason for the prescription, should be a real national concern (almost 0.7 boxes/women/year). 16.6k members in the AlternativeHealth community. If the results show that TSH is high and T-4 is low, then the diagnosis . Thank you for bringing it to our attention. video where the doc is talking about the study , i wlll link study and video below. 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