The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. y in life hysterectomy. Hypophosphatemia after an iron infusion is quite rare. And the medicines i take may have interferred with it is my only guess as to why this happened. We want the forums to be a useful resource for our users but it is important to remember that the forums are I personally usually advise people to stick to RDA level vitamins and if they want to go higher with B6 (based on labs), to stay under 10mg which I still think is a reasonable level of caution considering all the evidence. Vitamin B12 As a general rule of thumb, take your B vitamins in the morning or with a meal. do Provision of B12 allows repair to begin but the actual healing process itself is open-ended (months to years) depending on how much damage has been done. Folic acid works closely with vitamin B12 in making red blood cells and helps iron function properly in the body and your B12 levels were below the bottom of the range. Born and raised in the bustling city of New York, Sandra has always been drawn to the idea of living a balanced and fulfilling life. I am no expert on any of this but read this forum every day. People diagnosed with anaemia (including iron deficiency anaemia, sickle cell anaemia and thalassaemia). B12 tablets, probiotics, etc. I can appreciate the reasoning for not doing a B12 assay when checking her ferritin [or whatever iron indicator] but checking B12, Folate and Ferritin at the outset is probably wisest. as being in breach of those terms. Anaemia is where you have fewer red blood cells than normal or you have an abnormally low amount of a substance called haemoglobin in each red blood cell. Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked. Ill let you know my progress too. Fortunately she immediately started her on loading doses and has given her a prescription for B12 for self injection as she needs it. These cookies help provide information on metrics the number of visitors, bounce rate, traffic source, etc. Heres a verified case of adverse reactions to vitamin B12 shots due to benzyl alcohol sensitivity. It depends on your progress and how you respond to the injections. It seems you may need high B12 supplementation and to stop any folate supplements for a while. It's extremely unlikely such symptoms are B6 related. Had b12 low was on injections and had h pylori. UL refers to the maximum daily dose of a vitamin unlikely to cause adverse side effects in the general population. I sometimes liken it to a badly tuned radio on which you have turned the volume up high trying to catch the programme you want when all of a sudden the signal comes in loud and clear and the blast nearly deafens you. Urine: THC from edibles can be detected in a , Pumpkin seeds are rich in nutrients known to support weight loss, such as fiber, protein, and unsaturated fatty acids. What size needle do you need for B12 injection? And to get back to the point here, the original poster mentions a low B12 level and receiving treatment for same, but not taking any additional B vitamins so the simplest explanation here is that they are experiencing neurological damage from B12 deficiency, rather than anything to do with B6. Does anyone else feel worse after b12 injection. Someone once described it to me as the nerves starting to wake up after being starved of B12 for so long. Hi Quinny99 - how are you feeling now?I experience a huge spike in symptoms after an injection too. Also, the needle needs to be long enough to reach the muscle of the person youre injecting. Sadly my much improved digestion has gone downhill again. Performance cookies are used to understand and analyze the key performance indexes of the website which helps in delivering a better user experience for the visitors. Left untreated, a vitamin B-12 Non-existent B12 has to be a misprint or the test was not done. this seems to be quit good, has good results already, and is easy to take u just give it to yourself in the fat of your stomach and it is absolutely painless and that is coming from someone who does not like needles i was terrified but after they administered my first shot at my first appointment it was not bad at all.Read More Read Less, Routine test showed a B12 deficiency that was unreadable by local labs. Things I notice: more energy, improved stamina at the gym and on the field, increased appetite, results from workouts improving, mood improved, restful sleep, and I have lost a few pounds and kept it off easily. Also forgot to mention that I had an ECG my first time I went in and the doctor said it was normal, but I finally got to look at it and on the sheet it says slight inferior repolarization disturbance. I haven't felt much of a change in my migraines, but have noticed that I just haven't been feeling well overall on a day to day basis. So my guess its to do with my stomach? I'm currently struggling through a day at work and could really do with some peice of mind that this is normal and other people have felt like this? Injection You have both. B12 weekly vitamin B12 shots and after the first I felt great. To make sure your B12 is free of any additives, you may want to try a vial of our pure methyl B12. Good luck and I wish you well on your recovery xxx. B12 injections after If possible take someone with you who can validate your neurological symptoms as the doctor is less likely to pooh pooh you in front of a witness. Necessary cookies are absolutely essential for the website to function properly. Typically, 'less than 50' might be a response, depending on the method used and the laboratory. I was upset b/c when I returned after the first the nurse thought I'd feel cured. We cannot be held liable for our third-party providers. Migrains featured. However, people who follow a vegetarian or vegan diet might be prone to deficiency because plant foods don't contain vitamin B-12. I feel the same I don't feel any better my doctor thinks it's in my head as I should feel so much better I feel soow, How are you feeling now? Hi, so I have received my 6 shots of B12. Can you have any reactions or side effects from vitamin B12 injections? Heart palpitations: this could be anxiety - one of the many symptoms of B12 deficiency. was making sure every one was aware, all good. Hope you're feeling better! A few symptoms of B12 deficiency include: Conditions of the small intestine (Crohns disease), anemia, fatigue, constipation, poor balance, memory loss, shortness of breath, and more. Within in a couple of months her eczema was completely gone. Adverse Reactions to Vitamin B12 Shots - SFGATE You'll likely feel rubbish for the next few jabs. Make sure there is no air trapped inside and no blood when you pull on the syringe slightly. No prescription needed. I cant do much until I have some sort of diagnosis so I can sort myself out. The original poster's symptoms sound like normal B12 neurological recovery symptoms to me - similar to those experienced by me and many others here. Pain/redness at the injection site, mild diarrhea, itching, or a feeling of swelling all over the body may occur. People with a family history of pernicious anaemia. This time I felt anxious for about 10 mins that evening, tired and achy the next day, but that has been it. It is not uncommon for some symptoms to appear to get worse before they get better as the B12 you are having starts repairing the damage done to your nervous system and your brain starts getting multiple messages from part of the body it had "forgotten about" or lost contact with. Is vitamin B12 good for energy? Do NOT follow this link or you will be banned from the site! Its frustrating when no doctors can pinpoint on what the issues are. Feeling worse after B12 Injections - Pernicious Anaemi Also I was severely iron dificient. But, it feels equally bad while that happens (my experience, too) or maybe worse. Wow! Cant have everything I suppose! Had 3 injections per week from physician for 2 months, continuing to take 1cc injections IM per week at home. Hi there, Im in the same boat with B12 injection. I just need to sort myself out as its stopping me from going to University lectures and stuff like that. I have been battling migraines for two+ decades. This website uses cookies to improve your experience while you navigate through the website. Very comprehensive with lots of case studies. I now see improvement in some of my symptoms for a while but I quickly go back to how I originally felt if I have something like a headache or have missed a vitamin. the injection that they gave me has vitamin B-12, methione, inositol, and choline in it and was referred to as vitamin B-12 and MIC shot. Hi sorry, Im going to go for my first jab since the 6 lots of jabs. Recently I? i take vitamin b12 injection it has helped me tomaintain my weight & help termendously with stress. Depending on symptoms your GP should test for these too. But wait until you can feel all ten fingers and ten toes again, without weird sensations! Most absorption problems aren't treatable but a few are - notably h pylori infection - which would mean that once that has been dealt with you would be able to absorb B12 from your diet so wouldn't need maintenance shots for life. It's not always the case, but I would have expected something as well as an unmeasurable B12. This is great and I will continue the shots without question. Injections are simple and painless. 2005 - 2023 WebMD LLC, an Internet Brands company. Just a thought, have you had your ferritin checked? Draw vitamin B12 from the vial into your syringe. Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. e u just give it to yourself in the fat of your stomach and it is absolutely painless and that is coming from someone who does not like needles i was terrified but after they administered my first shot at my first appointment it was not bad at all. Learn How Genetics Make Some Fans of Fear, Dr. Whyte's Book: Take Control of Your Cancer Risk, How Breast Cancer Changed My Life and Me, Health News and Information, Delivered to Your Inbox. Im just hoping that this injection will make me better. Felt very dizzy and sick from around 20 mins after having the jab and then just extreame exhustion. There are lots of potential causes of B12 deficiency. But thing that I noticed tho is that it has helped me keep my weight down, but the side effects outweighed the benefits so I will not be getting another unless my doctor tells me I n. eed it. The only thing I can say is that my mum and nan both have anaemia, but I think its my ferritin levels that are low (theyre at 9) and thats why I have to take 3 iron tablets a day. What Is The Difference Between 'Active Vitamin B12' and 'Total Vitamin B12'? I have low B12 but not CD, and my son is the reverse. B12 may be injected into a muscle or under the skin at 100 mcg daily for a week, every other day for another week, and then every three or four days for a month. When her GP saw the results, she was shocked and told my daughter she had never seen a result for B12 like that. We can all agree that B6 is a possible cause of peripheral neuropathy but based on the limited information here, everything points to the neuropathy being from a B12 deficiency, not a B6 overdose. When in doubt, don't eat it. This cookie is set by GDPR Cookie Consent plugin. Vitamin B12 or folate deficiency anaemia - Treatment - NHS All rights reserved. I was fine until I took the shot, afterwards, it had caused mental changes as well as mood changes. However, its important to know what your levels are, after all, vitamin B12 deficiency can cause damage to your nerves and affect brain function. ?ve noticed a metallic taste after my injection. As with any advice, treatment or recommendation given by a physician or other healthcare provider, I urge everyone to do their own research, accurately report symptoms and/or satisfaction/tolerance, and determine what is best for you, your health, and your situation.Read More Read Less. B12 shots can help you to feel more energetic, fight lethargy, and can also help with mood.. getting the levels of iron and folate checked. I knowwe are left in the dark Docs don't care (maybe a few do, but in generally they don't) as they are not educated well enough to understand what impact this has on patients. I guess that your sharing of this article is to make the point that B12 deficiency may have a cause other than pernicious anemia. If you have Pernicious Aneamia then it is possible you have other autoimmune conditions, for instance Hashimotos (where the immune system attacks the thyroid), type 1 diabetes, Sjogrens Syndrome etc. Its the one that begins with an H (I cant spell it). And a cascade of varying head kains znd headaches. Began taking injections daily down to monthly. I felt better overall each week, but my symptoms still ebbed and flowed for a while. Dont fear the cases above. Fatigue, dizziness, paleness, and a rapid heart rate. If any of these effects last or get worse, tell your doctor or pharmacist B12 is needed to maintain and repair the myelin sheath that protects nerves. Read our editorial policy. The main reason why some people feel worse after their B12 injection is due to an increase in energy. I have had crying episodes that I did not have beforeso this vitamin injection did me little good. I am still tired (I take iron tablets 3 times a day). My right toe has residual numbness. Your body is damaged and will likely feel worse before you're all better. There may have been other things in the mix such as Iron etc, but its highly unlikely there's a B6 toxicity issue. I have had crying episodes that I did not have beforeso this vitamin injection did me little good. But I had my 6th on Hello! Other options include the deltoid muscle of the upper arm and the dorsogluteal site on the bottom. It comes 100% pure, no additives or preservatives whatsoever. If the b12 FERRITEN folate needs to be in balance us FERRITEN 40 to low ? But everyone reacts to everything differently. Today I am hurting all over. Some symptoms will "disappear" quite quickly whereas others may take months or even years. can all "gluten" you and stall your healing while making your worse, not better. People who regularly use proton-pump- inhibitors. Generally, the results of vitamin B12 injections can last about one week, but it is vital to have this administered by a healthcare provider. If its none of the things hes testing, he said its probably anxiety. Whatever the results, the complaint remains- the reason for juanpablo111 's initial visit to the walk-in clinic. Might be worth asking your doctors if they have checked your iron levels. Lastly, Ive been waking up from having leg cramps and my feet feel like theyre wanting to cramp constantly. Vitamin B12 or folate deficiency anaemia can cause a wide range of symptoms. Thank you so much!! People may lose patience as you sort it all out, but take all the time you need to stay well. Are you anybody better ? Why vitamin B 12 is important The human body needs vitamin B 12 to make red blood cells, nerves, DNA, and carry out other functions. Avoid strenuous exercise for 48 hours after your treatment. cystic acne breakouts by a dermatologist. Usually a dose of 0.25-0.5 mg/kg is sufficient. For me it took until the last jab until I felt better . And the B12 should help as well. Thereafter, 100 mcg should be injected once a month for life. But opting out of some of these cookies may affect your browsing experience. If you were a recovering alcholic, you'd have withdrawl symptoms, right? Any supplementation? Therefore, monitor these two, and you may want to increase your potassium intake in the first few months of injecting. So Im sure you will get there. Also, methyl B12 is the most absorbable form, with distinct nerve repairing properties. I went into the walk-in It can also cause anxiety, along with the low B12. Which it could be thats making all of the physical symptoms happen. MMA should drop once B12 is replete. I think the damage takes longer than the healing, maybe? Maybe have your doctor do it with our pure methyl B12, which again, nobody has ever reported any negative reaction to. When your body receives the B12 shot, it begins to absorb more of the nutrient than usual, which can cause a spike in energy levels. because obviously b12 medications are being used as a mere bandaid , 20yrs for some of you? It does get better, just make sure you get the next 2 or 3 monthly top up jabsI've had to pay privately for mine as nhs seem to think a reading of 305 is okwhen it's defiantly not. Whether its a mild rash, a cut, or an eczema flare irritated skin is inflamed and more likely to have a reaction. This includes the nerve cells(neurons) of the brain. Anyone staying below 25mg of B6 a day is unlikely to run into problems, let alone neurological symptoms (which are only seen at 100mg/day). It's now impossible to say whether that was true, or a placebo effect. Low iron can lead to smaller red blood cells (microcytosis). Some people can get a drop in potassium levels (hypokalaemia) when they start B12 treatment. Store the vials in a cool room. Some symptoms will "disappear" quite quickly whereas others may take months or even years. I thought I would feel better straight away, but I suspect Ive been low for years, and so it make sense that recovery might take time! It's important to stick to your b12 schedule . I have seen previous comments regarding successful weight loss, but this has not been my experience (even with diet and daily exercise). Benefits, sources & deficiencies, 9 Hidden Dangers of Taking Health Supplements, Vitamins, Supplements and Nutrition in Pregnancy. Martyn Hooper is the chair of PAS (Pernicious Anaemia Society). Posted Advertisement cookies are used to provide visitors with relevant ads and marketing campaigns. I have MTHFR mutation and wonder if this might be why they are not having a good effect on me. I only got a breakthrough with this one doctor who said that I needed a blood test. If I have any of this wrong, feel free to correct me (addressing more experienced members of this forum). I would respectfully ask if the B12 test could be repeated, I have learned here that B12 supplementing can alter folate levels so I wonder if your folate level being considerably above the high end of the range has masked your B12 deficiency and affected your B12 levels? B12 Injection Its good you are getting the B12 and take heart that it seems common to feel worse before you get better. Like it needs to be sorted because its affecting my everyday life. Plus get the inside scoop on our latest content and updates in our monthly newsletter. Call your doctor at once if you have: heart problems--swelling, rapid weight gain, feeling short of breath; fluid build-up in If youre injecting a premature newborn, avoid benzyl alcohol at all cost due to the risk of gasping syndrome. It can also cause testicular shrinkage and breast enlargement in men. If you search online for "Sally Pacholok B12 conference" it should show a link to a slideshow Sally presented to a conference in US. She had been diagnosed as iron deficient several years before but her doctor at that time didn't test her B12 level. Rhinitis (chronic sneezing or a congested, drippy nose). i will post further progress with this drug as my treatment furthers with it. I began B-12 injections 2 times per week and within one week noticed a dramatic improvement in my energy levels. These usually develop gradually but can worsen if the condition goes untreated. After the jabs I had like one month where I felt great, like I could go out running and Id be fine. I tend to get over excited at the thought of feeling better which then makes the disappintment when it doesnt happen much worse. I am 40 years old and was tired all of the time. (And all I have is the low B12) Didn't work like that for me! The cost for Vitamin B12 injectable solution (1000 mcg/mL) is around $90 for a supply of 25 milliliters, depending on the pharmacy you visit. B12 Deficiency is Serious Had I not gotten a third opinion, my situation could have potentially gotten worse. I had forgotten what it was like to have this kind of energy. However, once diagnosed it presents a difficult management problem in patients suffering from pernicious anemia, as there is no substitute. B12 is water-soluble, and its generally safe even at very high doses. Folate could be a problem too. Hi, I still get foot cramps and I have numbness in my left leg and left hand. Prices are for cash paying customers only and are not valid with insurance plans. Lifestyle factors such as heavy smoking and drinking or a poor diet over a prolonged period can also lead to low B12 levels or deficiency. PearlH -- not sure if you'll see this, but B6 lowers FOLATE. Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them. That is signalling something is wrong, despite blood results being good/erroneous. I have heard of people being told on this forum that their results were "below measurable" -but never that they were non-existant ! As you age, you produce less stomach acid, which is critical for the absorption of B12. Had 3 injections per week from physician for 2 months, continuing to take 1cc injections IM per week at home. After 6-8 months from the surgery the feeling began to come back, and accompanying the return of feeling there were shooting pains. Obviously I was worried by this, but told it was natural as the nerve endings re-joined. With low B12 the nerves aren't severed, but they are damaged. Sorry, that went before I'd finished typing! People who undergo surgeries or dental procedures involving nitrous oxide, or who use the drug recreationally. Since then it has been a real roller coaster ride. It is best to take a vitamin B12 test to determine if you have particular symptoms in the nervous system or have a vitamin b12 deficiency. An abnormal increase in red Heres a case of two female pernicious anemia patients who had negative reactions to hydroxy B12 shots. People who regularly use proton-pump- inhibitors. But I wont know until I get the blood test. I'm not convinced by the reports they provide that they have conclusive evidence of peripheral neuropathy from B6 at doses under 25mg. I'm curious about your overrange folate. Basically by pervious B12 deifciency symptoms just mych more intense. Im just worried that these symptoms may be because of the injections or something serious. Older adults and people with digestive tract conditions that affect absorption of nutrients also are susceptible to vitamin B-12 deficiency. My guess still remains that there's been an error in the process somewhere and it's 'crept out'. Major confusion, depression, and fatigue. They don't even hurt. So I was wondering if theres any conditions that may affect this? Who can and cannot have it Having your injection Side effects Pregnancy, breastfeeding and fertility Having it with other medicines and herbal supplements Common questions Related conditions. You're right Technoid. I always got some signal. Me too, feeling even worse than before the injections. B-12 Injection People with autoimmune disorders (especially thyroid disorders such as Hashimotos thyroiditis and Graves disease) Type 1 diabetes, vitiligo, lupus, Addisons disease, ulcerative colitis, infertility, acquired agammaglobulinemia, or a family history of these disorders. Because vitamin B12 plays a role in so many different functions in your body, a deficiency in the vitamin can manifest in many different ways and cause a wide array of You're absolutely right, the opportunity to investigate pre-treatment is almost certainly gone; some laboratories archive samples, but the amount of space required for the benefits returned makes that extremely unlikely. The shots don't bother me at all. Where is the best place to give a B12 injection? Out of these, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. Her doctor told her that because my daughter was so young she didn't think B12 deficiency was likely. It really means a lot that people are so helpful, it really does make a difference in all of this. I have seen previous comments regarding successful weight loss, but this has not been my experience (even with diet and daily exercise). To view profiles and participate in discussions please. Her eczema had spread to the soles of her feet and even though she was only in her early 20s she was hobbling around like an old lady. I am 40 years old and was tired all of the time. Avoid irritated skin and blood vessels. Typically, our patients experience positive effects between 24-72 hours after the treatment. No energy boost like I got from first few. A neurologist recently decided to test my Vitamin B 12 levels and determined that, although I was within the normal range, I had a deficiency that may be contributing to symptoms, possibly causing my migraines. Vitamin B-12 Injection: Uses, Side Effects, Interactions - WebMD People with digestive issues or celiac disease may not be able to process and absorb B12. Though rare, this reaction can cause muscle cramping, extreme fatigue, and an irregular heartbeat. Because vitamin B-12 is water soluble and lipotropic components are safe, you dont have to worry about getting too much. B12 is 659pg/mL and folate is the same (this was 4 days after my most recent injection), also taking a B-complex vitamin daily with 15mcg of b12 . Look for reactions such as skin rash, swelling, a blue tint to your skin, chest tightness, etc. I never read on the B-12 shot, but I received it yesterday at,12:30 pm and around 5 this morning I started with belly pain and diarrhea. Low B12 can lead to enlarged red blood cells (macrocytosis). Welzo acts as a healthcare platform, connecting patients with the best healthcare providers to enable a seamless experience. WebMD does not provide medical advice, diagnosis or treatment. What is the relation between b12 deficiency and weight gain? But back then I did not realise how the vitamins work together and was only taking folic acid. Normally even high dose B6 complexes are not allowed to provide B6 over 25mg, which is the tolerable upper limit. That was big for me, and it's how I found this site in the first place (I'm in the US). If you get the blood results Im sure that will help. Again, in my case, it's my son. If you order your B12 shots anywhere else, make sure it comes from a certified lab that follows stringent pharmacy regulations. The cookie is used to store the user consent for the cookies in the category "Performance". Laboratories [well, NHS labs in the UK] have very sophisticated error-trapping routines. And the medicines i take may have interferred with it is my only guess as to why this happened.Read More Read Less. )?how often? You are so right about mourning my healthy self, i never looked at it like that before, i do miss her at the moment haha. If your serum B12 level was 0 then I'm guessing you feel really ill. So am still not feeling great and was hoping the B12 would improve it. I have B6 toxicity, P.A. Patient does not provide medical advice, diagnosis or treatment. Injection Side Effects and When to Seek Medical Help - Verywell If youre sure the B12 was pure, then the next question would be, was the correct fluid added to the vial? "but I do find it weird that my B12 is nonexistent and yet my RBC, MCV, and MCH are normal.". To view profiles and participate in discussions please. Do you keep B12 injections in the fridge? I just had my first shot after the loading doses three days ago. Next one is aimed at health professionals in US. Apply a cold compress. Analytical cookies are used to understand how visitors interact with the website. It just seems that the doctor doesnt take all of this seriously or thinks that I am making all of it up. Vitamin B12 or folate deficiency anaemia My son was a different person within 4 months (had 2nd worst category of villus atrophy so he was young but far gone at age 6! People with Crohns disease, irritable bowel syndrome, gluten enteropathy (celiac disease), or any other disease that cause malabsorption of nutrients.